Reaction Details |
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Target | Eukaryotic translation initiation factor 4E |
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Ligand | BDBM167334 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Binding Assay |
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pH | 7±n/a |
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IC50 | 1200±n/a nM |
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Comments | extracted |
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Citation | Gillespie, P Benzoic acid derivatives US Patent US9073881 Publication Date 7/7/2015 |
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More Info.: | Get all data from this article, Assay Method |
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Eukaryotic translation initiation factor 4E |
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Name: | Eukaryotic translation initiation factor 4E |
Synonyms: | EIF4E | EIF4EL1 | EIF4F | Eukaryotic translation initation factor | Eukaryotic translation initiation factor 4E (eIF4E) | Eukaryotic translation initiation factor 4E/Eukaryotic translation initiation factor 4E-binding protein 1 | IF4E_HUMAN |
Type: | Protein |
Mol. Mass.: | 25095.44 |
Organism: | Homo sapiens (Human) |
Description: | P06730 |
Residue: | 217 |
Sequence: | MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
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BDBM167334 |
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n/a |
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Name | BDBM167334 |
Synonyms: | US9073881, 84 |
Type | Small organic molecule |
Emp. Form. | C20H11Cl2N3O3S |
Mol. Mass. | 444.291 |
SMILES | OC(=O)c1cc(ccc1-c1cnc(O)nc1)-c1nc(cs1)-c1ccc(Cl)c(Cl)c1 |
Structure |
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