| Reaction Details |
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 | Report a problem with these data |
| Target | Atrial natriuretic peptide receptor 3 |
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| Ligand | BDBM287919 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Vasoreactivity in Rat Mesenteric Arteries In Vitro |
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| EC50 | >50000±n/a nM |
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| Citation |  Selwood, D; Hobbs, A Agents for use in the treatment of cardiovascular and inflammatory diseases structurally based on 4(1 H)-quinolone US Patent US10087144 Publication Date 10/2/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Atrial natriuretic peptide receptor 3 |
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| Name: | Atrial natriuretic peptide receptor 3 |
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| Synonyms: | ANP-C | ANPR-C | ANPRC | ANPRC_MOUSE | Atrial natriuretic peptide C-type receptor | Atrial natriuretic peptide clearance receptor | Atrial natriuretic peptide receptor 3 | Atrial natriuretic peptide receptor C | EF-2 | NPR-C | Npr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59812.13 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_35004 |
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| Residue: | 536 |
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| Sequence: | MRSLLLFTFSACVLLARVLLAGGASSGAGDTRPGSRRRAREALAAQKIEVLVLLPRDDSY
LFSLARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARG
AKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMG
EMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNFDETKDLDLD
DIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGMTSGDYAFFNIELFNSSSYGDGSWRRG
DKHDSEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEEDYVNMFVEGFHDAI
LLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVVAMTDTE
AGTQEVIGDYFGKEGRFQMRSNVKYPWGPLKLRLDETRIVEHTNSSPCKSSGGLEESAVT
GIVVGALLGAGLLMAFYFFRKKYRITIERRNQQEESNIGKHRELREDSIRSHFSVA
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| BDBM287919 |
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| n/a |
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| Name | BDBM287919 |
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| Synonyms: | US10087144, Compound 119 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21BrN2O4 |
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| Mol. Mass. | 457.317 |
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| SMILES | CC(C)C(NC(=O)c1cn(Cc2ccccc2)c2ccc(Br)cc2c1=O)C(O)=O |
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| Structure | 
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