| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-synuclein |
|---|
| Ligand | BDBM50157562 |
|---|
| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Binding Assay |
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| pH | 7.4±n/a |
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| Ki | 1100±n/a nM |
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| Comments | extracted |
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| Citation |  Luke, EA; Yadon, MC; Cummings, J; Hudson, FM; Lake, T; Hu, Q; Cam, J; Snow, AD Compounds for the treatment of neurodegenerative diseases US Patent US9085549 Publication Date 7/21/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-synuclein |
|---|
| Name: | Alpha-synuclein |
|---|
| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
|
|
|
|---|
| BDBM50157562 |
|---|
| n/a |
|---|
| Name | BDBM50157562 |
|---|
| Synonyms: | 1,3-bis(3,4-dihydroxyphenyl)prop-2-en-1-one | 3,3',4,4'-tetrahydroxychalcone | CHEMBL225618 | US9085549, 94 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C15H12O5 |
|---|
| Mol. Mass. | 272.2528 |
|---|
| SMILES | Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2)cc1O |
|---|
| Structure | 
|
|---|
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