Reaction Details |
| Report a problem with these data |
Target | Protease |
---|
Ligand | BDBM171365 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Inhibition Assay |
---|
Ki | 5±n/a nM |
---|
Citation | Ghosh, AK Nonpeptide HIV-1 protease inhibitors US Patent US9085571 Publication Date 7/21/2015 |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Protease |
---|
Name: | Protease |
Synonyms: | n/a |
Type: | Enzyme |
Mol. Mass.: | 10904.79 |
Organism: | Human immunodeficiency virus 1 (HIV-1) |
Description: | Q9YQ12 |
Residue: | 99 |
Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM171365 |
---|
n/a |
---|
Name | BDBM171365 |
Synonyms: | US9085571, Table 1, Compound 13 |
Type | Small organic molecule |
Emp. Form. | C39H53N5O5 |
Mol. Mass. | 671.8686 |
SMILES | CN(Cc1nc(C)oc1C)C(=O)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C |r| |
Structure |
|