| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1B3 |
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| Ligand | BDBM172717 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Uptake Transporter Assay |
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| pH | 7.3±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 1800±n/a nM |
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| Comments | extracted |
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| Citation |  Gregory, MA; Moss, SJ; Wilkinson, B Compound and methods for its production US Patent US9090657 Publication Date 7/28/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1B3 |
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| Name: | Solute carrier organic anion transporter family member 1B3 |
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| Synonyms: | LST2 | OATP1B3 | OATP8 | Organic Anion Transporter OATP1B3 | SLC21A8 | SLCO1B3 | SO1B3_HUMAN | Solute carrier organic anion transporter family member 1B3 | Solute carrier organic anion transporter family member 1B3 (OATP1B3) |
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| Type: | Protein |
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| Mol. Mass.: | 77425.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NPD5 |
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| Residue: | 702 |
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| Sequence: | MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFD
ISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGY
YRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNML
RGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYV
DLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK
TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVF
KYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFL
FQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGIT
YLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAI
QVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM
KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASD
NERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAAAN
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| BDBM172717 |
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| n/a |
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| Name | BDBM172717 |
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| Synonyms: | US9090657, 24 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H62FN5O11 |
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| Mol. Mass. | 867.9991 |
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| SMILES | CC(C)[C@@H]1NC(=O)[C@H](CCC(C)=O)[C@H](O)[C@@H](C)[C@@H](O)\C=C\C=C\C[C@H](OC(=O)C2CCCN(N2)C(=O)[C@H](Cc2cc(O)cc(F)c2)NC1=O)C(\C)=C\C=C\C(=O)N1CCCCO1 |r,t:19,21| |
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| Structure | 
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