| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 2 [E165G] |
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| Ligand | BDBM22360 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro Cyclooxygenase (COX) Inhibition Assay |
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| IC50 | >1.00e+5±n/a nM |
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| Citation |  Abdellatif, KR; Elshemy, HA; Azoz, AA 1-(4-Methane(amino)sulfonylphenyl)-3-(4-substituted-phenyl)-5-(4-trifluoromethylphenyl)-1H-2-pyrazolines/pyrazoles as potential anti-inflammatory agents. Bioorg Chem63:13-23 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin G/H synthase 2 [E165G] |
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| Name: | Prostaglandin G/H synthase 2 [E165G] |
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| Synonyms: | COX2 | Cyclooxygenase-2 (COX-2) | PGH2_HUMAN | PTGS2 |
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| Type: | Protein |
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| Mol. Mass.: | 68932.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35354[E165G] |
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| Residue: | 604 |
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| Sequence: | MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFL
TRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADY
GYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVGKLLLRRKFIPDPQGS
NMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKY
QIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQ
NRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRV
AGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEAL
YGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEV
GFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKER
STEL
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| BDBM22360 |
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| n/a |
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| Name | BDBM22360 |
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| Synonyms: | 2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid | Acetylsalicylic acid | Aspirin | Endosprin | Polopirin | Zorprin | acetylsalicylate | cid_2244 |
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| Type | Anti-Inflammatory Agents, Non-Steroidal |
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| Emp. Form. | C9H8O4 |
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| Mol. Mass. | 180.1574 |
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| SMILES | CC(=O)Oc1ccccc1C(O)=O |
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| Structure | 
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