| Reaction Details |
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 | Report a problem with these data |
| Target | Acyl-CoA desaturase 1 |
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| Ligand | BDBM60550 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 6±n/a nM |
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| Comments | extracted |
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| Citation |  Yang, S; Kuo, G; Gaul, MD; Rano, TA Substituted piperidinyl-pyridazinyl derivatives useful as SCD 1 inhibitors US Patent US9102669 Publication Date 8/11/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Acyl-CoA desaturase 1 |
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| Name: | Acyl-CoA desaturase 1 |
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| Synonyms: | ACOD1_RAT | Acyl-CoA desaturase 1 | Scd | Scd1 | Stearoyl-CoA desaturase 1 (SCD1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41485.97 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P07308 |
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| Residue: | 358 |
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| Sequence: | MPAHMLQEISSSYTTTTTITEPPSGNLQNGREKMKKVPLYLEEDIRPEMREDIHDPSYQD
EEGPPPKLEYVWRNIILMALLHVGALYGITLIPSSKVYTLLWGIFYYLISALGITAGAHR
LWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSH
VGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGET
FLHSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYH
HAFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAVLARIKRTGDGSHKSS
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| BDBM60550 |
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| n/a |
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| Name | BDBM60550 |
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| Synonyms: | BDBM50448682 | US9102669, 53 |
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| Type | n/a |
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| Emp. Form. | C23H22F2N4 |
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| Mol. Mass. | 392.4444 |
|---|
| SMILES | Fc1ccc(cc1)-c1ccc(nn1)N1CCC(CC1)N1CCc2ccc(F)cc12 |
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| Structure | 
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