| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oligo-1,6-glucosidase IMA1 |
|---|
| Ligand | BDBM175310 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Baker's Yeast α-Glucosidase Inhibition Assay |
|---|
| pH | 6.8±n/a |
|---|
| IC50 | 9.99e+3± 6.9e+2 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Zawawi, NK; Taha, M; Ahmat, N; Wadood, A; Ismail, NH; Rahim, F; Azam, SS; Abdullah, N Benzimidazole derivatives as new a-glucosidase inhibitors and in silico studies. Bioorg Chem64:29-36 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oligo-1,6-glucosidase IMA1 |
|---|
| Name: | Oligo-1,6-glucosidase IMA1 |
|---|
| Synonyms: | α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68577.59 |
|---|
| Organism: | Saccharomyces cerevisiae S288c (Baker's yeast) |
|---|
| Description: | n/a |
|---|
| Residue: | 589 |
|---|
| Sequence: | MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWIS
PFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWF
KESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCS
TQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQS
SDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSEL
FNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRF
GDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIK
EEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGIN
VEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAA
LNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
|
|
|
|---|
| BDBM175310 |
|---|
| n/a |
|---|
| Name | BDBM175310 |
|---|
| Synonyms: | (E)-N'-(2,3-dihydroxybenzylidene)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)benzohydrazide (5) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H20N4O3 |
|---|
| Mol. Mass. | 400.4299 |
|---|
| SMILES | Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1cccc(O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
