| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vascular endothelial growth factor receptor 3 [818-948,1003-1077] |
|---|
| Ligand | BDBM176598 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Biochemical Assay |
|---|
| pH | 7.4±n/a |
|---|
| IC50 | 240±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Holmes, IP; Bergman, Y; Lunniss, GE; Nikac, M; Chol, N; Hemley, CF; Walker, SR; Foitzik, RC; Ganame, D; Lessene, R Selective FAK inhibitors US Patent US9120761 Publication Date 9/1/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vascular endothelial growth factor receptor 3 [818-948,1003-1077] |
|---|
| Name: | Vascular endothelial growth factor receptor 3 [818-948,1003-1077] |
|---|
| Synonyms: | FLT4 | VEGFR3 | VGFR3_HUMAN | modified VEGFR3 cytoplasmic domain |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 34324.27 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35916[818-948,1003-1077] |
|---|
| Residue: | 306 |
|---|
| Sequence: | DPGEVPLEEQCEYLSYDASQWEFPRERLHLGRVLGYGAFGKVVEASAFGIHKGSSCDTVA
VKMLKEGATASEHRALMSELKILIHIGNHLNVVNLLGACTKPQGPLMVIVEFCKYGNLSN
FLRAKRDAFSPDLWLSPLTMEDLVCYSFQVARGMEFLASRKCIHRDLAARNILLSESDVV
KICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLG
ASPYPGVQINEEFCQRLRDGTRMRAPELATPAIRRIMLNCWSGDPKARPAFSELVEILGD
LLQGRG
|
|
|
|---|
| BDBM176598 |
|---|
| n/a |
|---|
| Name | BDBM176598 |
|---|
| Synonyms: | US9120761, 12 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H32F3N5O |
|---|
| Mol. Mass. | 511.5818 |
|---|
| SMILES | CN1CCC(CC1)c1ccc(Nc2ncc(c(CCc3ccccc3CC(N)=O)n2)C(F)(F)F)c(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
