| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase TEM |
|---|
| Ligand | BDBM178170 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cell Free Inhibition Assay |
|---|
| pH | 7±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | 1.8±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Bulusu, AR Substituted clavulanic acid US Patent US9120808 Publication Date 9/1/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase TEM |
|---|
| Name: | Beta-lactamase TEM |
|---|
| Synonyms: | BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 31512.33 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P62593 |
|---|
| Residue: | 286 |
|---|
| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
|---|
| BDBM178170 |
|---|
| n/a |
|---|
| Name | BDBM178170 |
|---|
| Synonyms: | US9120808, Example 49 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H11NO6 |
|---|
| Mol. Mass. | 253.2081 |
|---|
| SMILES | CC1C\C(C(=O)O1)=C1/O[C@@H]2CC(=O)N2C1C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
