| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM178180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cell Free Inhibition Assay |
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| pH | 7±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 6450.2±n/a nM |
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| Comments | extracted |
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| Citation |  Bulusu, AR Substituted clavulanic acid US Patent US9120808 Publication Date 9/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
|
|
|
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| BDBM178180 |
|---|
| n/a |
|---|
| Name | BDBM178180 |
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| Synonyms: | US9120808, Example 59 |
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| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18INO5 |
|---|
| Mol. Mass. | 455.2437 |
|---|
| SMILES | ICC1CC(CO1)=C1O[C@@H]2CC(=O)N2C1C(=O)OCc1ccccc1 |r,w:4.4,2.1| |
|---|
| Structure | 
|
|---|
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