| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 |
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| Ligand | BDBM179557 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Surface plasmon resonance (SPR) |
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| IC50 | 294.715±n/a nM |
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| Citation |  Visser, MS; Yusuff, N Compounds for inhibiting the interaction of BCL2 with binding partners US Patent US9126980 Publication Date 9/8/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Apoptosis regulator Bcl-2 |
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| Name: | Apoptosis regulator Bcl-2 |
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| Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
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| Type: | Homodimer or heterodimer |
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| Mol. Mass.: | 26269.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10415 |
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| Residue: | 239 |
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| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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| BDBM179557 |
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| n/a |
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| Name | BDBM179557 |
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| Synonyms: | US9126980, 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H41N5O5S |
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| Mol. Mass. | 595.753 |
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| SMILES | CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(C)(=O)=O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| |
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| Structure | 
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