Reaction Details |
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Target | Apoptosis regulator Bcl-2 |
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Ligand | BDBM179576 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Surface plasmon resonance (SPR) |
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IC50 | 1053.175±n/a nM |
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Citation | Visser, MS; Yusuff, N Compounds for inhibiting the interaction of BCL2 with binding partners US Patent US9126980 Publication Date 9/8/2015 |
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More Info.: | Get all data from this article, Assay Method |
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Apoptosis regulator Bcl-2 |
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Name: | Apoptosis regulator Bcl-2 |
Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
Type: | Homodimer or heterodimer |
Mol. Mass.: | 26269.11 |
Organism: | Homo sapiens (Human) |
Description: | P10415 |
Residue: | 239 |
Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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BDBM179576 |
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n/a |
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Name | BDBM179576 |
Synonyms: | US9126980, 21 |
Type | Small organic molecule |
Emp. Form. | C39H46N6O4S |
Mol. Mass. | 694.885 |
SMILES | CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2cccc3ccn(C)c23)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| |
Structure |
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