| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM179909 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | n/a |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 0.41±n/a nM |
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| IC50 | 0.45±0.06 nM |
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| Comments | extracted |
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| Citation |  Blumberg, LC; Deaver, D; Eyerman, D Morphan and morphinan analogues, and methods of use US Patent US9133125 Publication Date 9/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
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|
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| BDBM179909 |
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| n/a |
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| Name | BDBM179909 |
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| Synonyms: | US9133125, Table D, buprenorphine |
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| Type | Small organic molecule |
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| Emp. Form. | C29H41NO4 |
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| Mol. Mass. | 467.6401 |
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| SMILES | CO[C@@H]1C([C@H]2CC[C@@]11Oc3c4c(C[C@@H]5C2[C@]14CCN5CC1CC1)ccc3O)[C@](C)(O)C(C)(C)C |r| |
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| Structure | 
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