| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-dependent insulinotropic receptor |
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| Ligand | BDBM180595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AlphaScreen cAMP Assay |
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| pH | 7.4±n/a |
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| Temperature | 310.15±n/a K |
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| EC50 | 142±n/a nM |
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| Comments | extracted |
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| Citation |  Grauert, M; Bakker, R; Breitfelder, S; Buettner, F; Eickelmann, P; Fox, T; Grundl, M; Lehmann-Lintz, T; Rist, W Benzoxazole- and tetrahydrobenzoxazole-substituted pyridazinones as GPR119 agonists US Patent US8772323 Publication Date 7/8/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucose-dependent insulinotropic receptor |
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| Name: | Glucose-dependent insulinotropic receptor |
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| Synonyms: | G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor |
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| Type: | Protein |
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| Mol. Mass.: | 36901.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDV5 |
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| Residue: | 335 |
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| Sequence: | MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISG
LLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGF
VAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLL
FVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTP
FLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKV
LTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
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| BDBM180595 |
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| n/a |
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| Name | BDBM180595 |
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| Synonyms: | US8772323, 185 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20ClN3O2 |
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| Mol. Mass. | 381.855 |
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| SMILES | CCC[C@@H]1[C@@H](C)C(=NNC1=O)c1ccc2nc(oc2c1)-c1ccc(Cl)cc1 |r,c:6| |
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| Structure | 
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