| Reaction Details |
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 | Report a problem with these data |
| Target | Endothelial lipase |
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| Ligand | BDBM181701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Assay |
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| pH | 8±n/a |
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| IC50 | <10±n/a nM |
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| Comments | extracted |
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| Citation |  Pi, Z; Qiao, JX; Tora, GO; Wang, TC Amide or urea containing benzothiazole inhibitors of endothelial lipase US Patent US9139578 Publication Date 9/22/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Endothelial lipase |
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| Name: | Endothelial lipase |
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| Synonyms: | EDL | EL | Endothelial cell-derived lipase | LIPE_HUMAN | LIPG |
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| Type: | Protein |
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| Mol. Mass.: | 56805.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y5X9 |
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| Residue: | 500 |
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| Sequence: | MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPE
HEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVV
VDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGN
FVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHID
IYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDS
NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKN
MGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGAS
QSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWF
RKCRDGWRMKNETSPTVELP
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| BDBM181701 |
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| n/a |
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| Name | BDBM181701 |
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| Synonyms: | US9139578, 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27N5O4S |
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| Mol. Mass. | 505.589 |
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| SMILES | CC(=O)NC(c1nnc(o1)C1CN(C1)C(=O)OC(C)(C)C)c1nc2ccc(cc2s1)-c1ccccc1 |
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| Structure | 
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