Reaction Details |
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Target | P2X purinoceptor 3 |
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Ligand | BDBM183238 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibition Assay |
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pH | 7.5±n/a |
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Temperature | 310.15±n/a K |
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IC50 | 10±n/a nM |
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Comments | extracted |
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Citation | Kai, H; Kameyama, T; Hasegawa, T; Oohara, M; Tada, Y; Endoh, T Triazine derivative and pharmaceutical composition comprising the same US Patent US9150546 Publication Date 10/6/2015 |
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More Info.: | Get all data from this article, Assay Method |
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P2X purinoceptor 3 |
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Name: | P2X purinoceptor 3 |
Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa |
Type: | Protein |
Mol. Mass.: | 44292.02 |
Organism: | Homo sapiens (Human) |
Description: | P56373 |
Residue: | 397 |
Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
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BDBM183238 |
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n/a |
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Name | BDBM183238 |
Synonyms: | US9150546, I-408 | US9688643, I-408 | US9718790, I-0407 |
Type | Small organic molecule |
Emp. Form. | C25H29ClN4O5 |
Mol. Mass. | 500.975 |
SMILES | CC(C)Oc1ccc(cc1Cl)\N=c1/[nH]c(=O)n(CC(C)(C)C(O)=O)c(=O)n1Cc1ccc(C)cc1 |
Structure |
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