| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein-glutamine gamma-glutamyltransferase 2 |
|---|
| Ligand | BDBM185756 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Inhibition Assay |
|---|
| IC50 | 28500±2400 nM |
|---|
| Citation |  Pardin, C; Keillor, JW; Lubell, WD Cinnamoyl inhibitors of transglutaminase US Patent US9162991 Publication Date 10/20/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein-glutamine gamma-glutamyltransferase 2 |
|---|
| Name: | Protein-glutamine gamma-glutamyltransferase 2 |
|---|
| Synonyms: | TGM2 | TGM2_CAVCU | Transglutaminases (TGase) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 77122.36 |
|---|
| Organism: | Cavia cutleri (Guinea pig) |
|---|
| Description: | P08587 |
|---|
| Residue: | 690 |
|---|
| Sequence: | MAEDLILERCDLQLEVNGRDHRTADLCRERLVLRRGQPFWLTLHFEGRGYEAGVDTLTFN
AVTGPDPSEEAGTMARFSLSSAVEGGTWSASAVDQQDSTVSLLLSTPADAPIGLYRLSLE
ASTGYQGSSFVLGHFILLYNPRCPADAVYMDSDQERQEYVLTQQGFIYQGSAKFINGIPW
NFGQFEDGILDICLMLLDTNPKFLKNAGQDCSRRSRPVYVGRVVSAMVNCNDDQGVLQGR
WDNNYSDGVSPMSWIGSVDILRRWKDYGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN
FNSAHDQNSNLLIEYFRNESGEIEGNKSEMIWNFHCWVESWMTRPDLEPGYEGWQALDPT
PQEKSEGTYCCGPVPVRAIKEGHLNVKYDAPFVFAEVNADVVNWIRQKDGSLRKSINHLV
VGLKISTKSVGRDEREDITHTYKYPEGSEEEREAFVRANHLNKLATKEEAQEETGVAMRI
RVGQNMTMGSDFDIFAYITNGTAESHECQLLLCARIVSYNGVLGPVCSTNDLLNLTLDPF
SENSIPLHILYEKYGDYLTESNLIKVRGLLIEPAANSYVLAERDIYLENPEIKIRVLGEP
KQNRKLIAEVSLKNPLPVPLLGCIFTVEGAGLTKDQKSVEVPDPVEAGEQAKVRVDLLPT
EVGLHKLVVNFECDKLKAVKGYRNVIIGPA
|
|
|
|---|
| BDBM185756 |
|---|
| n/a |
|---|
| Name | BDBM185756 |
|---|
| Synonyms: | US9162991, 4b |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N4O3 |
|---|
| Mol. Mass. | 356.4189 |
|---|
| SMILES | CCCCCCCCn1cc(nn1)C(=O)\C=C\c1ccc(cc1)N(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
