| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
|---|
| Ligand | BDBM186937 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Binding Assay |
|---|
| pH | 7.4±n/a |
|---|
| Ki | 6448±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K Morpholino compounds, uses and methods US Patent US9079895 Publication Date 7/14/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1D adrenergic receptor |
|---|
| Name: | Alpha-1D adrenergic receptor |
|---|
| Synonyms: | ADA1D_MOUSE | Adra1a | Adra1d | Alpha-1 adrenergic receptor | Gpcr8 | adrenergic Alpha2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 59890.14 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P97714 |
|---|
| Residue: | 562 |
|---|
| Sequence: | MTFRDILSVTFEGPRASSSTGGSGAGGGAGTVGPEGPAVGGVPGATGGSAVVGTGSGEDN
QSSTAEAGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRH
LQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWPFGRTFCDVWAAVDVLCCTASILS
LCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFC
GITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRI
HCRGAATSAKGNPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFF
VLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR
RLWPSLRPPLASLDRRPALRLCPQPAHRTPRGSPSPHCTPRPGLRRHAGGAGFGLRPSKA
SLRLREWRLLGPLQRPTTQLRAKVSSLSHKFRSGGARRAETACALRSEVEAVSLNVPQDG
AEAVICQAYEPGDLSNLRETDI
|
|
|
|---|
| BDBM186937 |
|---|
| n/a |
|---|
| Name | BDBM186937 |
|---|
| Synonyms: | US9079895, 25s |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H28N2O3 |
|---|
| Mol. Mass. | 368.4693 |
|---|
| SMILES | COc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc34)CCO2)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
