| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
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| Ligand | BDBM26741 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Assay |
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| pH | 9±n/a |
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| IC50 | 23±n/a nM |
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| Comments | extracted |
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| Citation |  Apodaca, R; Breitenbucher, JG; Pattabiraman, K; Seierstad, M; Xiao, W Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase US Patent US9169224 Publication Date 10/27/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 |
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| Name: | Fatty-acid amide hydrolase 1 |
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| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 63071.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00519 |
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| Residue: | 579 |
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| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
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| BDBM26741 |
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| n/a |
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| Name | BDBM26741 |
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| Synonyms: | N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide | PF-622 | US9169224, 19 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22N4O |
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| Mol. Mass. | 346.4256 |
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| SMILES | O=C(Nc1ccccc1)N1CCN(Cc2ccc3ccccc3n2)CC1 |
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| Structure | 
|
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