| Reaction Details |
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 | Report a problem with these data |
| Target | Sonic hedgehog protein |
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| Ligand | BDBM189265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Gli-Luc Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | <5000±n/a nM |
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| Comments | extracted |
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| Citation |  Guicherit, OM; Rubin, L Mediators of hedgehog signaling pathways, compositions and uses related thereto US Patent US9173869 Publication Date 11/3/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sonic hedgehog protein |
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| Name: | Sonic hedgehog protein |
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| Synonyms: | Hhg1 | SHH_MOUSE | Shh |
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| Type: | Protein |
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| Mol. Mass.: | 47784.50 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q62226 |
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| Residue: | 437 |
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| Sequence: | MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGAS
GRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPG
VKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKA
HIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLAADDQGRLLYSDFL
TFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAPHNDSGPTPGPSALFASRVRPGQR
VYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAH
RAFAPFRLAHALLAALAPARTDGGGGGSIPAAQSATEARGAEPTAGIHWYSQLLYHIGTW
LLDSETMHPLGMAVKSS
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| BDBM189265 |
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| n/a |
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| Name | BDBM189265 |
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| Synonyms: | US9173869, 45 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25Cl2N5O2 |
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| Mol. Mass. | 474.383 |
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| SMILES | CCC(N1CCN(C(C)C1)C(=O)Nc1ccc(Cl)c(Cl)c1)c1nc2ccccc2c(=O)[nH]1 |
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| Structure | 
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