| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2) |
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| Ligand | BDBM60812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Enzyme Assay |
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| IC50 | >100000±n/a nM |
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| Citation |  Hoffman, CS; Ceyhan, O Inhibitors of phosphodiesterase 11 (PDE11) US Patent US9173884 Publication Date 11/3/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2) |
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| Name: | Isoform PDE2A2 of cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2) |
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| Synonyms: | PDE2A | PDE2A_HUMAN | Phosphodiesterase 2A (PDE2A2) | cGMP-dependent 3',5'-cyclic phosphodiesterase (PDE2A2) |
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| Type: | Protein |
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| Mol. Mass.: | 105121.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00408-3 |
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| Residue: | 934 |
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| Sequence: | MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRAV
KEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSDL
PGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLVA
LRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQL
KVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQ
LKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQ
HCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNA
EICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLF
YRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGIS
IAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTP
RSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHF
CYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVME
RHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG
YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEM
MDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGL
PSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
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| BDBM60812 |
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| n/a |
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| Name | BDBM60812 |
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| Synonyms: | BDBM86641 | US9173884, BC11-28 |
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| Type | n/a |
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| Emp. Form. | C25H19FN4 |
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| Mol. Mass. | 394.4436 |
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| SMILES | Cc1ccccc1Nc1ncnc2n(cc(-c3ccccc3)c12)-c1ccc(F)cc1 |
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| Structure | 
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