| Reaction Details |
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 | Report a problem with these data |
| Target | Glutaminyl-peptide cyclotransferase-like protein |
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| Ligand | BDBM190694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Spectrophotometric Assay |
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| Temperature | 303.15±n/a K |
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| Ki | 100±n/a nM |
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| IC50 | 470±n/a nM |
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| Comments | extracted |
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| Citation |  Heiser, U; Ramsbeck, D; Hoffmann, T; Boehme, L; Demuth, H Inhibitors of glutaminyl cyclase US Patent US9181233 Publication Date 11/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Glutaminyl-peptide cyclotransferase-like protein |
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| Name: | Glutaminyl-peptide cyclotransferase-like protein |
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| Synonyms: | Glutaminyl Cyclase | Glutaminyl-peptide cyclotransferase-like protein (QC) | QPCTL | QPCTL_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 42941.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NXS2 |
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| Residue: | 382 |
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| Sequence: | MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGSAFYTIWSGWHRRTE
ELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFLE
ATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPPGSTP
FVGATDSAVPCALLLELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGS
RHLAQLMESIPHSPGPTRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLH
RLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNL
HPPTVHNLCRILAVFLAEYLGL
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| BDBM190694 |
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| n/a |
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| Name | BDBM190694 |
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| Synonyms: | US9181233, 85 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19N5O2 |
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| Mol. Mass. | 349.3865 |
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| SMILES | COc1ccc(CCn2cc(nn2)-c2ccc3[nH]cnc3c2)cc1OC |
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| Structure | 
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