| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 [I248L] |
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| Ligand | BDBM191061 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 10.3±1.5 nM |
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| Comments | extracted |
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| Citation |  Jacobson, KA; Tosh, DK Adenosine receptor agonists, partial agonists, and antagonists US Patent US9181253 Publication Date 11/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Adenosine receptor A3 [I248L] |
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| Name: | Adenosine receptor A3 [I248L] |
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| Synonyms: | AA3R_HUMAN | ADORA3 | Adenosine receptor A3 | Adenosine receptor A3 (A3) |
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| Type: | Protein |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8[I248L] |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSLINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM191061 |
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| n/a |
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| Name | BDBM191061 |
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| Synonyms: | US9181253, 123 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21ClFN5O3 |
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| Mol. Mass. | 433.864 |
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| SMILES | O[C@H]1C[C@]2(C[C@H]2[C@H]1O)n1cnc2c(NCc3ccccc3OCCF)nc(Cl)nc12 |r| |
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| Structure | 
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