| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-2 |
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| Ligand | BDBM192539 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PIM Enzyme Assay |
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| IC50 | 0.5±n/a nM |
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| Citation |  D'amico, DC; Herberich, BJ; Jackson, CL; Pettus, LH; Tasker, A; Wang, H; Wu, B; Wurz, R Bicyclic pyridazine compounds as Pim inhibitors US Patent US9187486 Publication Date 11/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-2 |
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| Name: | Serine/threonine-protein kinase pim-2 |
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| Synonyms: | PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2) |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 34185.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9P1W9 |
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| Residue: | 311 |
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| Sequence: | MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
GPAPLAWSLLP
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| BDBM192539 |
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| n/a |
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| Name | BDBM192539 |
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| Synonyms: | US9187486, 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21F2N7 |
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| Mol. Mass. | 421.4458 |
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| SMILES | N[C@H]1CCCN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1c(F)cccc1F |r| |
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| Structure | 
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