| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine protease 1 |
|---|
| Ligand | BDBM193314 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| pH | 8±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 0.29±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Fujiyasu, J; Ohne, K; Yamaki, S; Imaizumi, T; Hondo, T; Matsuura, K; Satou, T; Sasamura, S Guanidinobenzoic acid compound US Patent US9199927 Publication Date 12/1/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine protease 1 |
|---|
| Name: | Serine protease 1 |
|---|
| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26557.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07477 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
|
|
|
|---|
| BDBM193314 |
|---|
| n/a |
|---|
| Name | BDBM193314 |
|---|
| Synonyms: | US9199927, 25 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H23F3N4O5 |
|---|
| Mol. Mass. | 528.4798 |
|---|
| SMILES | NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](Cc2ccccc2)C(O)=O)c(c1)C(F)(F)F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
