| Reaction Details |
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 | Report a problem with these data |
| Target | Hypoxanthine phosphoribosyltransferase |
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| Ligand | BDBM194491 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Spectrophotometric Assay |
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| pH | 7.4±n/a |
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| Ki | 11000±600 nM |
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| Comments | extracted |
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| Citation |  De Jersey, J; Guddat, LW; Hockova, D; Keough, DT 6-oxopurine phosphoribosyltransferase inhibitors US Patent US9200020 Publication Date 12/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Hypoxanthine phosphoribosyltransferase |
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| Name: | Hypoxanthine phosphoribosyltransferase |
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| Synonyms: | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) |
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| Type: | Enzyme |
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| Mol. Mass.: | 26972.31 |
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| Organism: | Plasmodium vivax |
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| Description: | A0A0J9TE27 |
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| Residue: | 233 |
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| Sequence: | MKIPNNPGAGENALEPIYIKDDDGYDIDTFLIPDHYKNYITKVLIPNGVLKNRIEKLAFD
IKQVYRNEEFHVICLLKGSRGFFSALLKYLNRIHNYSSTESPKHLYVEHYVRVKSYCNDQ
SLDRIEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCEYLKKFEVKTIAITCLFIKRTPL
WNGFKADFVGFSIPDAFVVGYSLDYNEKFRDLDHLCLVNDEGIKKFRTAPPTA
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| BDBM194491 |
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| n/a |
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| Name | BDBM194491 |
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| Synonyms: | US9200020, Table 1, Compound 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H16N6O4P |
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| Mol. Mass. | 303.2349 |
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| SMILES | Nc1nc2n(CCNCCP(O)(O)=O)c[nH]c2c(=O)[nH]1 |
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| Structure | 
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