| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM194646 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Fluorescence Assay |
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| pH | 7.5±n/a |
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| IC50 | >100000±n/a nM |
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| Comments | extracted |
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| Citation |  Durham, TB; Marimuthu, J; Wiley, MR Aggrecanase inhibitors US Patent US9206139 Publication Date 12/8/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM194646 |
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| n/a |
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| Name | BDBM194646 |
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| Synonyms: | US9206139, 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22F3N3O3 |
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| Mol. Mass. | 397.3915 |
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| SMILES | CC(C)(Cc1ccc(cc1)C(F)(F)F)C(=O)NC[C@]1(NC(=O)NC1=O)C1CC1 |r| |
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| Structure | 
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