| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 6 [440-798] |
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| Ligand | BDBM198122 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC6 fluorescence anisotropy assay |
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| Temperature | 298.15±n/a K |
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| Ki | 350±50 nM |
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| IC50 | 600±90 nM |
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| Comments | extracted |
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| Citation |  Hai, Y; University of Pennsylvania,, DW Histone deacetylase 6 structure and molecular basis of catalysis and inhibition Nat Chem Biol12:741-747 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 6 [440-798] |
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| Name: | Histone deacetylase 6 [440-798] |
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| Synonyms: | Catalytic domain 2 (zCD2) | zCD2 |
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| Type: | n/a |
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| Mol. Mass.: | 39850.25 |
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| Organism: | Danio rerio |
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| Description: | F8W4B7[440-798] |
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| Residue: | 359 |
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| Sequence: | SSPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPARLATEEEL
ALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCALLAAGSCFNSAQAILTG
QVRNAVAIVRPPGHHAEKDTACGFCFFNTAALTARYAQSITRESLRVLIVDWDVHHGNGT
QHIFEEDDSVLYISLHRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYM
AAFHHLVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLI
ILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHAPFWSSLR
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| BDBM198122 |
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| n/a |
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| Name | BDBM198122 |
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| Synonyms: | HC toxin |
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| Type | Small organic molecule |
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| Emp. Form. | C21H32N4O6 |
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| Mol. Mass. | 436.502 |
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| SMILES | C[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCCC(=O)[C@@H]2CO2)NC(=O)[C@@H](C)NC1=O |
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| Structure | 
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