| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 5 |
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| Ligand | BDBM196841 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 320±0 nM |
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| Citation |  Oshima, K; Matsumura, S; Yamabe, H Nitrogen-containing compounds and pharmaceutical compositions thereof for the treatment of atrial fibrillation US Patent US9212187 Publication Date 12/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 5 |
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| Name: | Potassium voltage-gated channel subfamily A member 5 |
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| Synonyms: | HK2 | HPCN1 | KCNA5 | KCNA5_HUMAN | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.5 |
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| Type: | Enzyme |
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| Mol. Mass.: | 67222.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22460 |
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| Residue: | 613 |
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| Sequence: | MEIALVPLENGGAMTVRGGDEARAGCGQATGGELQCPPTAGLSDGPKEPAPKGRGAQRDA
DSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQ
RVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDGILYYYQ
SGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKEEEKPLPRNEFQRQVWLIF
EYPESSGSARAIAIVSVLVILISIITFCLETLPEFRDERELLRHPPAPHQPPAPAPGANG
SGVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFTFELLVRFFACPSKAGFSRNIMNII
DVVAIFPYFITLGTELAEQQPGGGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGL
QILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADNQGTHFSSIPDAFWWAVVTMTT
VGYGDMRPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDHEEPAVLKEEQG
TQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENADSARRGSCPLEKCNVKAKSNVDLRRSL
YALCLDTSRETDL
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| BDBM196841 |
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| n/a |
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| Name | BDBM196841 |
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| Synonyms: | US9212187, 43 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N4O2 |
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| Mol. Mass. | 442.5527 |
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| SMILES | CCn1c2ccc(OCCCN(CCc3cccnc3)Cc3ccncc3)cc2ccc1=O |
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| Structure | 
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