| Reaction Details |
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 | Report a problem with these data |
| Target | F420-dependent glucose-6-phosphate dehydrogenase [W44Y] |
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| Ligand | BDBM197175 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Binding Assay |
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| pH | 7±n/a |
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| Kd | 1170±170 nM |
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| Comments | extracted |
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| Citation |  Oyugi, MA; Bashiri, G; Baker, EN; Johnson-Winters, K Investigating the Reaction Mechanism of F420-Dependent Glucose-6-phosphate Dehydrogenase from Mycobacterium tuberculosis: Kinetic Analysis of the Wild-Type and Mutant Enzymes. Biochemistry55:5566-5577 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| F420-dependent glucose-6-phosphate dehydrogenase [W44Y] |
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| Name: | F420-dependent glucose-6-phosphate dehydrogenase [W44Y] |
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| Synonyms: | F420-dependent glucose-6-phosphate dehydrogenase mutant (FGD W44Y) | FGD_MYCTO | fgd | fgd1 |
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| Type: | Protein |
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| Mol. Mass.: | 36958.32 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WNE0[W44Y] |
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| Residue: | 336 |
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| Sequence: | MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPYRHQGGHAPFSLSWMTA
VGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPNRVFLGVGTGEALNEIATGYEG
AWPEFKERFARLRESVGLMRQLWSGDRVDFDGDYYRLKGASIYDVPDGGVPVYIAAGGPA
VAKYAGRAGDGFICTSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPE
LALNNTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQY
VTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
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| BDBM197175 |
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| n/a |
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| Name | BDBM197175 |
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| Synonyms: | F420 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N5O18P |
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| Mol. Mass. | 773.5926 |
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| SMILES | C[C@H](OP(O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)Cn1c2cc(=O)ccc2cc2c1[nH]c(=O)[nH]c2=O)C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O |
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| Structure | 
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