| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
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| Ligand | BDBM199949 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | <10000±n/a nM |
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| Citation |  Pohlki, F; Lange, U; Amberg, W; Ochse, M; Behl, B; Hutchins, CW Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy US Patent US9227930 Publication Date 1/5/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
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| Name: | Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
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| Synonyms: | Glycine Transporter 1 (GlyT1) | SC6A9_HUMAN | SLC6A9 | Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
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| Type: | Protein |
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| Mol. Mass.: | 70591.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48067-2 |
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| Residue: | 633 |
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| Sequence: | MVGKGAKGMLNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRN
GGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIG
IYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH
LLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSG
KVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLG
CAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVA
DHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWI
LQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGH
RNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIG
FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS
PEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
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| BDBM199949 |
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| n/a |
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| Name | BDBM199949 |
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| Synonyms: | US9227930, 196 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N4O5S |
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| Mol. Mass. | 498.595 |
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| SMILES | CCOC(=O)NC1Cc2ccc(OCCNS(=O)(=O)c3nccn3C)cc2C1Cc1ccccc1 |
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| Structure | 
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