Reaction Details |
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Target | Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
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Ligand | BDBM199956 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Radioligand Binding Assay |
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Ki | <100±n/a nM |
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Citation | Pohlki, F; Lange, U; Amberg, W; Ochse, M; Behl, B; Hutchins, CW Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy US Patent US9227930 Publication Date 1/5/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
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Name: | Isoform GlyT-1A of Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
Synonyms: | Glycine Transporter 1 (GlyT1) | SC6A9_HUMAN | SLC6A9 | Sodium- and chloride-dependent glycine transporter 1 (GlyT-1A) |
Type: | Protein |
Mol. Mass.: | 70591.43 |
Organism: | Homo sapiens (Human) |
Description: | P48067-2 |
Residue: | 633 |
Sequence: | MVGKGAKGMLNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRN
GGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIG
IYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSH
LLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSG
KVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLG
CAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVA
DHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWI
LQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGH
RNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIG
FLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAPTIAPS
PEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
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BDBM199956 |
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n/a |
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Name | BDBM199956 |
Synonyms: | US9227930, 203 |
Type | Small organic molecule |
Emp. Form. | C26H31FN4O3S |
Mol. Mass. | 498.613 |
SMILES | CC1CN(C1)C1Cc2cc(F)c(OCCNS(=O)(=O)c3cn(C)cn3)cc2C1Cc1ccccc1 |
Structure |
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