| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-1 |
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| Ligand | BDBM200027 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay |
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| IC50 | 1600±n/a nM |
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| Citation |  Evans, DM; Davie, RL; Edwards, HJ; Rooker, DP Benzylamine derivatives as inhibitors of plasma kallikrein US Patent US9234000 Publication Date 1/12/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-1 |
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| Name: | Kallikrein-1 |
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| Synonyms: | KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein |
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| Type: | Enzyme |
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| Mol. Mass.: | 28874.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06870 |
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| Residue: | 262 |
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| Sequence: | MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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| BDBM200027 |
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| n/a |
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| Name | BDBM200027 |
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| Synonyms: | US9234000, 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27Cl2F3N4O2 |
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| Mol. Mass. | 567.43 |
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| SMILES | NCc1ccc(CNC(=O)[C@H](Cc2ccc(Cl)c(Cl)c2)NC(=O)[C@H](N)Cc2ccc(cc2)C(F)(F)F)cc1 |
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| Structure | 
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