| Reaction Details |
|---|
 | Report a problem with these data |
| Target | WD repeat-containing protein 5 [24-334] |
|---|
| Ligand | BDBM200666 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
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| pH | 6.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | <1000±n/a nM |
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| Comments | extracted |
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| Citation |  Wang, S; Karatas, H; Dou, Y; Townsend, E; Bernard, D Inhibition of WDR5 interaction with its binding partners US Patent US9233086 Publication Date 1/12/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
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| |
| WD repeat-containing protein 5 [24-334] |
|---|
| Name: | WD repeat-containing protein 5 [24-334] |
|---|
| Synonyms: | BIG3 | WD repeat-containing protein 5 (WDR5) | WDR5 | WDR5_HUMAN |
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| Type: | n/a |
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| Mol. Mass.: | 34198.55 |
|---|
| Organism: | Homo sapiens (Human) |
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| Description: | N-terminal His-tagged WDR5Delta23 (residues 24-334) |
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| Residue: | 311 |
|---|
| Sequence: | TQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI
SGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNL
IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG
QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF
ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEN
DKTIKLWKSDC
|
|
|
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| BDBM200666 |
|---|
| n/a |
|---|
| Name | BDBM200666 |
|---|
| Synonyms: | US9233086, 3I |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H29N7O5 |
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| Mol. Mass. | 387.4347 |
|---|
| SMILES | C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(C)=O)C(N)=O |r| |
|---|
| Structure | 
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