| Reaction Details |
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 | Report a problem with these data |
| Target | Acyl-CoA desaturase 1 |
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| Ligand | BDBM50443712 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SCD1 Enzymatic Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 7±n/a nM |
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| Comments | extracted |
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| Citation |  Yang, S; Kuo, G; Gaul, MD; Rano, TA Substituted piperidinyl-carboxamide derivatives useful as SCD 1 inhibitors US Patent US9238658 Publication Date 1/19/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Acyl-CoA desaturase 1 |
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| Name: | Acyl-CoA desaturase 1 |
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| Synonyms: | ACOD1_RAT | Acyl-CoA desaturase 1 | Scd | Scd1 | Stearoyl-CoA desaturase 1 (SCD1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41485.97 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P07308 |
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| Residue: | 358 |
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| Sequence: | MPAHMLQEISSSYTTTTTITEPPSGNLQNGREKMKKVPLYLEEDIRPEMREDIHDPSYQD
EEGPPPKLEYVWRNIILMALLHVGALYGITLIPSSKVYTLLWGIFYYLISALGITAGAHR
LWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSH
VGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGLLLMCFILPTLVPWYCWGET
FLHSLFVSTFLRYTLVLNATWLVNSAAHLYGYRPYDKNIQSRENILVSLGAVGEGFHNYH
HAFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKKVSKAAVLARIKRTGDGSHKSS
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| BDBM50443712 |
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| n/a |
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| Name | BDBM50443712 |
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| Synonyms: | CHEMBL3093861 | US9238658, 33 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25FN4O2S |
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| Mol. Mass. | 416.512 |
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| SMILES | OC1CCc2nc(NC(=O)N3CCC(CC3)N3CCc4ccc(F)cc34)sc2C1 |
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| Structure | 
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