| Reaction Details |
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 | Report a problem with these data |
| Target | Probable manganese-dependent inorganic pyrophosphatase |
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| Ligand | BDBM205467 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric Malachite Green Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | >6.00e+5±n/a nM |
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| Comments | extracted |
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| Citation |  Pang, AH; Garzan, A; Larsen, MJ; McQuade, TJ; Garneau-Tsodikova, S; Tsodikov, OV Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis. ACS Chem Biol11:3084-3092 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable manganese-dependent inorganic pyrophosphatase |
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| Name: | Probable manganese-dependent inorganic pyrophosphatase |
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| Synonyms: | Inorganic pyrophosphatase (SaPPiase) | PPAC_STAAR | ppaC |
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| Type: | Protein |
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| Mol. Mass.: | 34052.80 |
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| Organism: | Staphylococcus aureus (Firmicutes) |
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| Description: | Q6GFD7 |
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| Residue: | 309 |
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| Sequence: | MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPE
LLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTA
TILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKY
GLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLA
VSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIV
PQITEALTK
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| BDBM205467 |
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| n/a |
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| Name | BDBM205467 |
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| Synonyms: | PPiase inhibitor, 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26ClN5 |
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| Mol. Mass. | 383.918 |
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| SMILES | CCCCN(CCCC)c1nc(Cl)nc(n1)-c1cccn1-c1ccccc1 |
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| Structure | 
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