| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50213098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Beta1-AR Binding Assay |
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| pH | 7.8±n/a |
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| Temperature | 277.15±n/a K |
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| Ki | 14750±2510 nM |
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| Comments | extracted |
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| Citation |  Wainer, IW; Bernier, M; Toll, LR; Jimenez, LA Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas US Patent US9492405 Publication Date 11/15/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
|
|
|
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| BDBM50213098 |
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| n/a |
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| Name | BDBM50213098 |
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| Synonyms: | (R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, Compound (R,R)-1 | US9492405, (R,R)-1 | US9492405, 28 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO4 |
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| Mol. Mass. | 303.3529 |
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| SMILES | C[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |
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| Structure | 
|
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