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TargetAlpha-synuclein
LigandBDBM207910
Substrate/Competitorn/a
Meas. Tech.In Vitro Inhibition Assay
EC50 111±n/a nM
Citation Griffioen, GVan Dooren, TRojas De La Parra, VAllasia, SMarchand, AKilonda, AChaltin, P Compounds for the treatment of neurodegenerative diseases US Patent US9266832 Publication Date 2/23/2016
More Info.:Get all data from this article,  Assay Method
 
Alpha-synuclein
Name:Alpha-synuclein
Synonyms:NACP | PARK1 | SNCA | SYUA_HUMAN
Type:Protein
Mol. Mass.:14451.42
Organism:Homo sapiens (Human)
Description:P37840
Residue:140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM207910
n/a
NameBDBM207910
Synonyms:US9266832, Cpd067
TypeSmall organic molecule
Emp. Form.C24H19ClF2N2O
Mol. Mass.424.87
SMILESFc1cc(F)cc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1
Structure
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