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TargetAlpha-synuclein
LigandBDBM207934
Substrate/Competitorn/a
Meas. Tech.In Vitro Inhibition Assay
EC50 581±n/a nM
Citation Griffioen, GVan Dooren, TRojas De La Parra, VAllasia, SMarchand, AKilonda, AChaltin, P Compounds for the treatment of neurodegenerative diseases US Patent US9266832 Publication Date 2/23/2016
More Info.:Get all data from this article,  Assay Method
 
Alpha-synuclein
Name:Alpha-synuclein
Synonyms:NACP | PARK1 | SNCA | SYUA_HUMAN
Type:Protein
Mol. Mass.:14451.42
Organism:Homo sapiens (Human)
Description:P37840
Residue:140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM207934
n/a
NameBDBM207934
Synonyms:US9266832, Cpd091
TypeSmall organic molecule
Emp. Form.C25H22ClFN2O
Mol. Mass.420.906
SMILESCn1cc(CCNC(=O)c2ccc(Cc3cccc(F)c3)cc2)c2cc(Cl)ccc12
Structure
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