Reaction Details | |||
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Target | Prostaglandin D2 receptor 2 | ||
Ligand | BDBM210754 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Binding Assay | ||
pH | 7.4±n/a | ||
Temperature | 323.15±n/a K | ||
Ki | 18.74±n/a nM | ||
Comments | extracted | ||
Citation | Huang, X; Palani, A; Rao, AU; Zhang, H; Zhou, W Substituted isoquinolines as CRTH2 receptor modulators US Patent US9290454 Publication Date 3/22/2016 | ||
More Info.: | Get all data from this article, Assay Method | ||
Prostaglandin D2 receptor 2 | |||
Name: | Prostaglandin D2 receptor 2 | ||
Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) | ||
Type: | Enzyme | ||
Mol. Mass.: | 43295.45 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q9Y5Y4 | ||
Residue: | 395 | ||
Sequence: |
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BDBM210754 | |||
n/a | |||
Name | BDBM210754 | ||
Synonyms: | US9290454, 3.6 | US9290454, 3.7 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H29FN2O5 | ||
Mol. Mass. | 516.5601 | ||
SMILES | COc1ccccc1-n1c(CCCCC(O)=O)cc2cc(ccc2c1=O)C(=O)N[C@H](C)c1ccc(F)cc1 |wD:29.32,(2.67,6.16,;2.67,4.62,;4,3.85,;5.33,4.62,;6.67,3.85,;6.67,2.31,;5.33,1.54,;4,2.31,;2.67,1.54,;1.33,2.31,;1.33,3.85,;,4.62,;-1.33,3.85,;-2.67,4.62,;-4,3.85,;-4,2.31,;-5.33,4.62,;,1.54,;;-1.33,-.77,;-1.33,-2.31,;,-3.08,;1.33,-2.31,;1.33,-.77,;2.67,,;4,-.77,;-2.67,-3.08,;-4,-2.31,;-2.67,-4.62,;-1.33,-5.39,;,-4.62,;-1.33,-6.93,;,-7.7,;,-9.24,;-1.33,-10.01,;-1.33,-11.55,;-2.67,-9.24,;-2.67,-7.7,)| | ||
Structure |