| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
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| Ligand | BDBM119398 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pim Kinase Binding Activity |
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| pH | 7.2±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 0.010±n/a nM |
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| Comments | extracted |
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| Citation |  Wang, X Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use US Patent US9573943 Publication Date 2/21/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Serine/threonine-protein kinase pim-3 |
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| Name: | Serine/threonine-protein kinase pim-3 |
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| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
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| Type: | Protein |
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| Mol. Mass.: | 35888.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86V86 |
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| Residue: | 326 |
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| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
|
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|
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| BDBM119398 |
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| n/a |
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| Name | BDBM119398 |
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| Synonyms: | US8669361, 140 | US9573943, Example 140 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23F2N7OS |
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| Mol. Mass. | 447.505 |
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| SMILES | Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CCC[C@@H](N)CC1 |r| |
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| Structure | 
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