| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase XIAP [241-356] |
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| Ligand | BDBM213402 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | XIAP BIR3 & cIAP1 BIR3 Binding Assays (DELFIA) |
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| Temperature | 298.15±n/a K |
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| IC50 | 2879±n/a nM |
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| Comments | extracted |
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| Citation |  Reiser, U; Madden, J 6-Alkynyl Pyridine US Patent US9278978 Publication Date 3/8/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| E3 ubiquitin-protein ligase XIAP [241-356] |
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| Name: | E3 ubiquitin-protein ligase XIAP [241-356] |
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| Synonyms: | API3 | BIR3 domain of X-linked inhibitor of apoptosis protein | BIRC4 | E3 ubiquitin-protein ligase (XIAP-BIR3) | E3 ubiquitin-protein ligase XIAP BIR-3 | E3 ubiquitin-protein ligase XIAP BIR3 | IAP3 | X chromosome-linked inhibitor of apoptosis BIR3 domain (XIAP BIR3) | X-linked inhibitor of apoptosis protein BIR3 domain (XIAP BIR-3) | XIAP | XIAP-BIR3 | XIAP_HUMAN | baculovirus IAP repeat 3 (BIR3) domain of XIAP |
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| Type: | Protein Binding Domain |
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| Mol. Mass.: | 13276.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | BIR3 of XIAP: RESIDUES 241-356. |
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| Residue: | 116 |
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| Sequence: | SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT
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| BDBM213402 |
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| n/a |
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| Name | BDBM213402 |
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| Synonyms: | US9278978, 37 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H30N8O |
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| Mol. Mass. | 518.6122 |
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| SMILES | CCNC(CC)C(=O)Nc1cc(cc(n1)C#Cc1ccc2c(C)nccc2c1)-c1ncnc2c(C)nn(C)c12 |
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| Structure | 
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