| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [44-168] |
|---|
| Ligand | BDBM215732 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | AlphaScreen Assay |
|---|
| IC50 | 27±n/a nM |
|---|
| Citation |  Engelhardt, H; Martin, L; Smethurst, C Pyridinones US Patent US9296748 Publication Date 3/29/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bromodomain-containing protein 4 [44-168] |
|---|
| Name: | Bromodomain-containing protein 4 [44-168] |
|---|
| Synonyms: | BET bromodomain 4(1) (BRD4(1)) | BRD4 | BRD4-BD1 protein (aa 44-168) | BRD4_HUMAN | Bromodomain protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 (BRD4) (aa 44-168) | Bromodomain-containing protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 bromodomain 1 (BRD4-BD1) | HUNK1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 14866.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | aa (44-168) |
|---|
| Residue: | 125 |
|---|
| Sequence: | NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKT
PMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE
LPTEE
|
|
|
|---|
| BDBM215732 |
|---|
| n/a |
|---|
| Name | BDBM215732 |
|---|
| Synonyms: | US9296748, II-19 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H27N5O2 |
|---|
| Mol. Mass. | 429.5142 |
|---|
| SMILES | C[C@@H](c1ccccc1)n1c(nc2cnc(cc12)N1CCOCC1)-c1cc(C)c(=O)n(C)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
