| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit alpha |
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| Ligand | BDBM215798 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Capillary Electrophoresis |
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| IC50 | 200±n/a nM |
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| Citation |  Jose, J; Götz, C; Gratz, A; Kuckländer, U Use of dibenzofuranone derivatives to inhibit kinases US Patent US9303005 Publication Date 4/5/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit alpha |
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| Name: | Casein kinase II subunit alpha |
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| Synonyms: | CK II | CK2 | CK2- alpha | CK2A1 | CSK21_HUMAN | CSNK2A1 | Casein kinase 2 | Casein kinase II (CK2) | Casein kinase II alpha/beta | Casein kinase II subunit alpha (CK2 alpha) | Casein kinase II subunit alpha (CK2A1) | Casein kinase II subunit alpha (CK2a I174A) | Casein kinase II subunit alpha (CK2a V66A) | Casein kinase II subunit alpha (CK2a dm V66I174AA) | Casein kinase II subunit alpha (CK2a) |
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| Type: | Enzyme |
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| Mol. Mass.: | 45151.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P68400 |
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| Residue: | 391 |
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| Sequence: | MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
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| BDBM215798 |
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| n/a |
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| Name | BDBM215798 |
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| Synonyms: | US9303005, Ric152 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12Cl2N2O4 |
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| Mol. Mass. | 367.183 |
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| SMILES | [#6]\[#6](-[#6])=[#6]\[#6](=O)-c1oc2c(Cl)c(Cl)c(-[#8]-[#6](-[#6])=O)c(C#N)c2c1-[#7] |
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| Structure | 
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