| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase II subunit alpha |
|---|
| Ligand | BDBM215799 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Capillary Electrophoresis |
|---|
| IC50 | 2400±n/a nM |
|---|
| Citation |  Jose, J; Götz, C; Gratz, A; Kuckländer, U Use of dibenzofuranone derivatives to inhibit kinases US Patent US9303005 Publication Date 4/5/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase II subunit alpha |
|---|
| Name: | Casein kinase II subunit alpha |
|---|
| Synonyms: | CK II | CK2 | CK2- alpha | CK2A1 | CSK21_HUMAN | CSNK2A1 | Casein kinase 2 | Casein kinase II (CK2) | Casein kinase II alpha/beta | Casein kinase II subunit alpha (CK2 alpha) | Casein kinase II subunit alpha (CK2A1) | Casein kinase II subunit alpha (CK2a I174A) | Casein kinase II subunit alpha (CK2a V66A) | Casein kinase II subunit alpha (CK2a dm V66I174AA) | Casein kinase II subunit alpha (CK2a) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 45151.12 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P68400 |
|---|
| Residue: | 391 |
|---|
| Sequence: | MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINIT
NNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTD
FKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAE
FYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYD
QLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDF
LDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPT
PSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
|
|
|
|---|
| BDBM215799 |
|---|
| n/a |
|---|
| Name | BDBM215799 |
|---|
| Synonyms: | US9303005, Ric138 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H10Cl2N2O5 |
|---|
| Mol. Mass. | 357.146 |
|---|
| SMILES | CCOC(=O)c1oc2c(Cl)c(Cl)c(OC(C)=O)c(C#N)c2c1N |
|---|
| Structure | 
|
|---|
Search and Browse
