| Reaction Details |
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 | Report a problem with these data |
| Target | Iodotyrosine deiodinase 1 [1-1,32-289] |
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| Ligand | BDBM217397 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IYD Binding Assay |
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| Kd | 1.410e+6± 7.0e+4 nM |
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| Citation |  Ingavat, N; Kavran, JM; Sun, Z; Rokita, SE Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase. Biochemistry56:1130-1139 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Iodotyrosine deiodinase 1 [1-1,32-289] |
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| Name: | Iodotyrosine deiodinase 1 [1-1,32-289] |
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| Synonyms: | C6orf71 | DEHAL1 | IYD | IYD1_HUMAN | Iodotyrosine deiodinase (IYD) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29825.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human IYD without its N-terminal transmembrane sequence (2-31 aa) |
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| Residue: | 259 |
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| Sequence: | MGEPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRS
QEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIR
KIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVH
YYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLLMLLPVGYPSK
EATVPDLKRKPLDQIMVTV
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| BDBM217397 |
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| n/a |
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| Name | BDBM217397 |
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| Synonyms: | 2-Iodophenol (2IP) |
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| Type | Small organic molecule |
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| Emp. Form. | C6H5IO |
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| Mol. Mass. | 220.0078 |
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| SMILES | Oc1ccccc1I |
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| Structure | 
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