| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1,4-galactosyltransferase 1 |
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| Ligand | BDBM222427 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | β-1,4-Galactosyltransferase I Assay |
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| pH | 5.4±n/a |
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| Temperature | 303.15±n/a K |
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| IC50 | 7.20e+5±n/a nM |
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| Comments | extracted |
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| Citation |  Pastuch-Gawolek, G; Plesniak, M; Komor, R; Byczek-Wyrostek, A; Erfurt, K; Szeja, W Synthesis and preliminary biological assay of uridine glycoconjugate derivatives containing amide and/or 1,2,3-triazole linkers. Bioorg Chem72:80-88 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1,4-galactosyltransferase 1 |
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| Name: | Beta-1,4-galactosyltransferase 1 |
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| Synonyms: | β-1,4-Galactosyltransferase I (β4GalT) | B4GALT1 | B4GT1_BOVIN | Beta-1,4-galactosyltransferase 1 | GALT | GGTB2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 44860.74 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | P08037 |
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| Residue: | 402 |
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| Sequence: | MKFREPLLGGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLRRLPQLVGVHPPL
QGSSHGAAAIGQPSGELRLRGVAPPPPLQNSSKPRSRAPSNLDAYSHPGPGPGPGSNLTS
APVPSTTTRSLTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGRYTPMDCISPH
KVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGESMFNRAKLLNVGFKEAL
KDYDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQ
FLSINGFPNNYWGWGGEDDDIYNRLAFRGMSVSRPNAVIGKCRMIRHSRDKKNEPNPQRF
DRIAHTKETMLSDGLNSLTYMVLEVQRYPLYTKITVDIGTPS
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| BDBM222427 |
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| n/a |
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| Name | BDBM222427 |
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| Synonyms: | 5'-deoxy-5'-[4-(β-D-glucopyranosyloxymethyl)-1,2-3-triazol-1-yl]uridine (5) |
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| Type | Small organic molecule |
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| Emp. Form. | C18H25N5O11 |
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| Mol. Mass. | 487.418 |
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| SMILES | OCC1O[C@@H](OCc2cn(C[C@H]3O[C@H](C(O)C3O)n3ccc(=O)[nH]c3=O)nn2)C(O)C(O)[C@@H]1O |r| |
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| Structure | 
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