| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dipeptidyl peptidase 3 |
|---|
| Ligand | BDBM50049391 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | DPP III Enzyme Activity Assay |
|---|
| pH | 7.4±0 |
|---|
| Temperature | 310.15±0 K |
|---|
| IC50 | 2.34e+4± 3e+3 nM |
|---|
| Citation |  Agic, D; Brkic, H; Tomic, S; Karacic, Z; ?poljarevic, M; Lisjak, M; Be?lo, D; Abramic, M Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach. Chem Biol Drug Des89:619-627 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dipeptidyl peptidase 3 |
|---|
| Name: | Dipeptidyl peptidase 3 |
|---|
| Synonyms: | DPP3 | DPP3_HUMAN | Dipeptidyl arylamidase III | Dipeptidyl peptidase 3 | Dipeptidyl peptidase III | Dipeptidyl peptidase III (DPP III) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 82565.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9NY33 |
|---|
| Residue: | 737 |
|---|
| Sequence: | MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIY
ALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPK
EKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMED
AKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFR
GSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFW
IQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWP
PTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQ
REKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPE
TGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIY
VNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPD
ARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRD
TVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLAT
ADARFWKGPSEAPSGQA
|
|
|
|---|
| BDBM50049391 |
|---|
| n/a |
|---|
| Name | BDBM50049391 |
|---|
| Synonyms: | 3,5,7-Trihydroxyflavone | 3,5,7-triOH-flavone | 3,5,7-trihydroxy-2-phenyl-4H-benzopyran-4-one | 3,5,7-trihydroxy-2-phenyl-4H-chromen-4-one | CHEMBL309490 | Galangin | Galangin (15) | Galangin (Gal) | cid_5281616 | norizalpinin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H10O5 |
|---|
| Mol. Mass. | 270.2369 |
|---|
| SMILES | Oc1cc(O)c2c(c1)oc(-c1ccccc1)c(O)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
