| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aldehyde dehydrogenase, dimeric NADP-preferring |
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| Ligand | BDBM223451 |
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| Substrate/Competitor | BDBM60953 |
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| Meas. Tech. | Inhibiton Assay |
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| pH | 7.5±n/a |
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| IC50 | 19600±3300 nM |
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| Comments | extracted |
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| Citation |  Hurley, TD Regulators of aldehyde dehydrogenase ALDH3A1 and related therapeutic methods US Patent US9320722 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Aldehyde dehydrogenase, dimeric NADP-preferring |
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| Name: | Aldehyde dehydrogenase, dimeric NADP-preferring |
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| Synonyms: | AL3A1_HUMAN | ALDH3 | ALDH3A1 | Aldehyde dehydrogenase 3A1 (ALDH3A1) | Aldehyde dehydrogenase family 3 member A1 (ALDH3A1) | Aldehyde dehydrogenase family 3 member A1 (ALDH3A1) (Q122A) |
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| Type: | Protein |
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| Mol. Mass.: | 50394.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 453 |
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| Sequence: | MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY
YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL
TIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKER
FDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNS
GQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEG
QKVAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREK
PLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFE
TFSHRRSCLVRPLMNDEGLKVRYPPSPAKMTQH
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| BDBM223451 |
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| BDBM60953 |
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| Name | BDBM223451 |
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| Synonyms: | US9320722, 12 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N3O5S |
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| Mol. Mass. | 378.422 |
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| SMILES | CC(C)C(=O)Nc1ccc(Nc2ccc(cc2[N+](O)=O)S(C)(=O)=O)cc1 |
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| Structure | 
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